2 Timothy 2:22

I. Paul here exhorts Timothy to beware of youthful lusts, Ti2 2:22. Though he was a holy good man, very much mortified to the world, yet Paul thought it necessary to caution him against youthful lusts: "Flee them, take all possible care and pains to keep thyself pure from them." The lusts of the flesh are youthful lusts, which young people must carefully watch against, and the best must not be secure. He prescribes an excellent remedy against youthful lusts: Follow righteousness, faith, charity peace, etc. Observe, 1. Youthful lusts are very dangerous, for which reason even hopeful young people should be warned of them, for they war against the soul, Pe1 2:11. 2. The exciting of our graces will be the extinguishing of our corruptions; the more we follow that which is good the faster and the further we shall flee from that which is evil. Righteousness, and faith, and love, will be excellent antidotes against youthful lusts. Holy love will cure impure lust. - Follow peace with those that call on the Lord. The keeping up of the communion of saints will take us off from all fellowship with unfruitful works of darkness. See the character of Christians: they are such as call on the Lord Jesus Christ, out of a pure heart. Observe, Christ is to be prayed to.

— Matthew Henry's Concise Commentary (public domain)

Flee--There are many lusts from which our greatest safety is in flight (Gen 39:12). Avoid occasions of sin. From the abstemious character of Timothy (Ti1 5:23) it is likely that not animal indulgences, but the impetuosity, rash self-confidence, hastiness, strife, and vainglory of young men (Jo1 2:14-16), are what he is here warned against: though the Spirit probably intended the warning to include both in its application to the Church in general. also--Greek, "But"; in contrast to "every good work," Ti2 2:21. youthful--Timothy was a youth (Ti1 4:12). righteousness--the opposite of "iniquity," that is, unrighteousness (Ti2 2:19; compare Ti1 6:11). peace, with, &c.--rather, put no comma, "peace with them that call on the Lord out of a pure heart" (Ti1 1:5; Eph 6:5; Col 3:22). We are to love all men, but it is not possible to be at peace with all men, for this needs community of purpose and opinion; they alone who call on the Lord sincerely (as contrasted with the false teachers who had only the form of godliness, Ti2 3:5, Ti2 3:8; Tit 1:15-16) have this community [THEODORET]. (Rom 12:18).

— Jamieson-Fausset-Brown Commentary (public domain)